M.J. and T.F. are cofounders and have equity ownership in Cantargia AB (Ideon To study the expression of LSC markers in more detail, IL1RAP, CD25 and.

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Cantargia is developing the humanised antibody CAN04, against the target molecule Interleukin-1 Receptor Associated Protein ("IL1RAP"), for treatment of cancer. Cantargia has previously shown that

556791-6019, är ett bioteknikbolag som utvecklar antikroppsbaserade behandlingar för livshotande sjukdomar. Den ursprungliga upptäckten från forskargruppen bakom Cantargia var ett överuttryck av en specifik målmolekyl, interleukin 1 receptor accessory protein “IL1RAP”, i leukemistamceller. Cantargia AB (publ), reg.no. 556791-6019, är ett bioteknikbolag som utvecklar antikroppsbaserade behandlingar för livshotande sjukdomar. Den ursprungliga upptäckten från forskargruppen bakom Cantargia var ett överuttryck av en specifik målmolekyl, interleukin 1 receptor accessory protein “IL1RAP”, i leukemistamceller. Om Cantargia Cantargia AB (publ), reg.no. 556791-6019, är ett bioteknikbolag som utvecklar antikroppsbaserade behandlingar för livshotande sjukdomar.

Cantargia il1rap

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The lead clinical trial is a Phase IIa CANFOUR study with CAN04 in non-small  IL1RAP is overexpressed on candidate AML stem cells and is a promising target for Cantargia AB is the owner of the intellectual property rights for agents  M.J. and T.F. are cofounders and have equity ownership in Cantargia AB (Ideon To study the expression of LSC markers in more detail, IL1RAP, CD25 and. 2 Jun 2019 Cantargia $CANTA CAN04 (anti-IL1RAP) phase I #ASCO19 1/4 good safety profile. 0% ORR/ 43% CBR for the dose-escalation monotherapy  CAN04 is a first-in-class fully humanized monoclonal antibody targeting IL1RAP, a co-receptor for the IL-1 receptor which is expressed on human cancer cells. 20 Oct 2016 In the new study Cantargia shows that high levels of IL1RAP are expressed also in several different solid tumours, including non-small cell lung  9 May 2018 antibody attaches to the IL1RAP receptor molecule and blocks it from Cantargia's lead candidate CAN04 targets the IL1RAP molecule and  15 Dec 2020 The basis for this is the protein IL1RAP that is involved in a number of diseases Cantargia is listed on Nasdaq Stockholm (ticker: CANTA). 2 May 2013 Cantargia AB is the owner of the intellectual property rights for agents targeting IL1RAP for use in the treatment and diagnosis of neoplastic  20 Oct 2018 Positive Phase I Clinical Data Presented for Cantargia's Nidanilimab targeting the Interleukin 1 Receptor Accessory Protein (IL1RAP), which  26 May 2019 2504Background: Interleukin 1 receptor Accessory protein, IL1RAP, is expressed in several solid tumors, both on cancer cells and  1 Feb 2021 Cantargia develops IL1RAP-targeting antibodies for treatment of cancer and inflammation and has reached clinical phase II in non-small cell  20 Aug 2020 Cantargia AB. September,. 2020.

Cantargia's vision is to develop and secure the new generation of targeted medicines against IL1RAP as an important part of tomorrow's more effective cancer treatments. The vision also includes developing new product candidates with the potential to treat even autoimmune / inflammatory diseases.

About Cantargia Cantargia AB (publ), reg. no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases.

Cantargia il1rap

10 mars 2020 — Forskningsbolaget Cantargia förvärvar en patentportfölj från Cellerant Therapeutics vilken täcker olika aspekter runt "interleukin 1 receptor 

The main project, Cantargia’s lead preclinical-stage anticancer candidate CAN04 is another IL1RAP-targeting anibody designed to activate immune system killer cells and block signals that lead to tumor growth.

Cantargia il1rap

Cantargia (Biotechnology) Cantargia AB (publ) is a biotechnology company that develops antibody-based treatments for life-threatening diseases.
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Cantargia il1rap

IL1RAP targeted antibodies in tumor forms not already covered in the European mother patent, which was granted in 2016. The current opponent, Mab Discovery GmbH, also filed an […] Cantargia's second project, currently in the research phase, is aimed at developing an IL1RAP-binding antibody that is optimised for treatment of autoimmune and inflammatory diseases. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

IL1RAP. Non Small Cell.
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14 nov. 2018 — cancercellerna med IL1RAP-uttryck. CAN04 är för närvarande i fas I och Cantargia kommer att kunna presentera slutresultat från den studien 

The lead project CAN04 is in phase IIa clinical development for treatment of cancer while CAN10 is in preclinical development towards autoimmunity/inflammatory diseases. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The lead project CAN04 is in phase IIa clinical development for treatment of cancer Besides the patents that Cantargia already owns, there is one additional patent on IL1RAP as target for antibody-based therapy in hematological cancer: US patent no. 8,715,619 from Cellerant Cantargia develops antibody-based pharmaceuticals against IL1RAP.